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Clinical Research

Contains posts about clinical research


Treatment of Refractory Diabetic Foot Ulcers Improved With LeucoPatch

In patients with diabetes who have hard-to-heal foot ulcers, a clinically and statistically significant benefit has been associated with the weekly application of autologous leukocytes, fibrin, and platelet patches (LeucoPatch), according to the results of a multicenter, randomized, controlled trial ( identifier: NCT02224742) published in The Lancet Diabetes & Endocrinology.

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Independent risk factors for pressure ulcer development in a high-risk nursing home population receiving evidence-based pressure ulcer prevention: Results from a study in 26 nursing homes in Belgium


The aim of this study was to identify independent risk factors for pressure ulcer (PU) development in a high‐risk nursing home population receiving evidence‐based PU prevention. This study was part of a randomised controlled trial examining the (cost‐)effectiveness of static air support surfaces compared with alternating pressure air mattresses.

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Fidgetin-Like 2 siRNA Enhances the Wound Healing Capability of a Surfactant Polymer Dressing

Microtubules (MTs) are intracellular polymers that provide structure to the cell, serve as railways for intracellular transport, and regulate many cellular activities, including cell migration. The dynamicity and function of the MT cytoskeleton are determined in large part by its regulatory proteins, including the recently discovered MT severing enzyme Fidgetin-like 2 (FL2).

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