News & Publications

Clinical Research

Contains posts about clinical research

Feb
18

Development and use of biomaterials as wound healing therapies

There is a vast number of treatments on the market for the management of wounds and burns, representing a multi-billion dollar industry worldwide. These include conventional wound dressings, dressings that incorporate growth factors to stimulate and facilitate the wound healing process, and skin substitutes that incorporate patient-derived cells.

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Feb
6

Pressure Ulcers: Prevention and Management

Prevention has been a primary goal of pressure ulcer research. Despite such efforts, pressure ulcers remain common in hospitals and the community. Moreover, pressure ulcers often become chronic wounds that are difficult to treat and tend to recur after healing.

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Feb
4

Microbial guardians of skin health

Skin, our largest and outermost organ, faces numerous challenges, including wounds, infections, inflammatory disorders, and cancer. Fortunately, it does not meet these challenges alone. Our skin is home to complex microbial communities, the skin microbiota, that play a fundamental role in the protection and control of this barrier surface.

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Jan
18

Biologically Inspired, Cell‐Selective Release of Aptamer‐Trapped Growth Factors by Traction Forces

Biomaterial scaffolds that are designed to incorporate dynamic, spatiotemporal information have the potential to interface with cells and tissues to direct behavior. Here, a bioinspired, programmable nanotechnology‐based platform is described that harnesses cellular traction forces to activate growth factors, eliminating the need for exogenous triggers (e.g., light), spatially diffuse triggers (e.g., enzymes, pH changes), or passive activation (e.g., hydrolysis).

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